岐阜薬科大学薬品化学研究室では有機化学基盤の環境調和型新規反応や触媒の開発及びそれらの医薬品化学?プロセス化学?環境科学への応用研究を行っています。
研究業績(学会抄録)
- Synthesis of deuterated benzyladenine and its application as a surrogate.
Nkaelang Modutlwa, Hiroyuki Tada, Yoshiki Sugahara, Koichi Shiraki, Nobuyuki Hara, Yoshihiro Deyashiki, Takayuki Ando, Tomohiro Maegawa, Yasunari Monguchi, and Hironao Sajiki
NUCLEIC ACIDS SYMP SER (OXF) (2009) 53: 105-106
- Alternative I-D exchange reaction on pyrimidine and purine nuclei mediated by tributyltin hydride using THF-d8 as a deuterium source.
Tomonobu Mutsumi, Kazuo Maruhashi, Yasunari Monguchi, and Hironao Sajiki
NUCLEIC ACIDS SYMP SER (OXF) (2009) 53: 3-4
- Modification of the sugar moiety in uridine via 2',3'-epoxyuridine derivatives.
Takasu, Hideki; Tsuji, Yoshie; Sajiki, Hironao; Hirota, Kosaku. Laboratory of Medicinal Chemistry, Gifu Pharmaceutical University, 5-6-1 Mitahora-higashi, Gifu, Japan.
Nucleic Acids Symposium Series (2004), 48, 49-50.
- Palladium-catalyzed H-D exchange into nucleic acids in deuterium oxide.
Sajiki, Hironao; Aoki, Fumiyo; Esaki, Hiroyoshi; Maegawa, Tomohiro; Hirota, Kosaku. Laboratory of Medicinal Chemistry, Gifu Pharmaceutical University, Gifu, Japan.
Nucleic Acids Research Supplement (2003), 3(3rd International Symposium on Nucleic Acids Chemistry [and] 30th Symposium on Nucleic Acids Chemistry in Japan, 2003), 55-56.
- A novel C-C bond formation at the 5-position of uridine derivatives.
Sajiki, Hironao; Yamada, Akira; Yasunaga, Kanoko; Tsunoda, Takashi; Amer, Mumen F. A.; Hirota, Kosaku. Laboratory of Medicinal Chemistry, Gifu Pharmaceutical University, Gifu, Japan.
Nucleic Acids Research Supplement (2002), 2(Twenty-ninth Symposium on Nucleic Acids Chemistry), 13-14.
- Synthesis of 2,3-dihydroinosine derivatives by reduction using BH3-THF.
Hirota Kosaku; Hattori R; Sajiki Hironao; Monguchi Yasunari; Muraoka Osamu; Tanabe Genzo Gifu Pharmaceutical University, Mitahora-higashi, Gifu 502-8585, Japan
Nucleic acids symposium series (2000), 44, 113-4.
- A novel C-C bond formation at the 5-position of uridine derivatives.
Sajiki, Hironao; Yamada, Akira; Yasunaga, Kanoko; Tsunoda, Takashi; Amer, Mumen F. A.; Hirota, Kosaku. Laboratory of Medicinal Chemistry, Gifu Pharmaceutical University, Gifu, Japan.
Nucleic Acids Research Supplement (2002), 2(Twenty-ninth Symposium on Nucleic Acids Chemistry), 13-14.
- Synthesis of 6-aminouracils and pyrrolo[2,3-d]pyrimidine-2,4-diones and their inhibitory effect on thymidine phosphorylase.
Hirota Kosaku; Sawada Masayuki; Sajiki Hironao; Sako Magoichi Laboratory of Medicinal Chemistry, Gifu Pharmaceutical University, Japan
Nucleic acids symposium series (1997), 37, 59-60.
- Synthesis of acyclonucleosides from purine nucleosides.
Monguchi, Yasunari; Kitade, Kitade; Sajiki, Hironao; Sako, Magoichi; Hirota, Kosaku. Lab. Med. Chem., Gifu Pharmaceutical Univ., Gifu, Japan.
Nucleic Acids Symposium Series (1996), 35(Twentythird Symposium on Nucleic Acids Chemistry, 1996), 51-52.
- Chemical modification of the sugar moiety in pyrimidine nucleosides via 2',3'-epoxy derivatives.
Hirota, Kosaku; Tsuji, Yoshie; Ohkubo, Tomohiro; Takasu, Hideki; Kitade, Yukio; Sako, Magoichi; Sajiki, Hironao. Lab. Medicinal Chem., Gifu Pharmaceutical Univ., Gifu, Japan.
Nucleic Acids Symposium Series (1996), 35(Twentythird Symposium on Nucleic Acids Chemistry, 1996), 47-48.
- Novel reactions of 5-bromouracil derivatives with active methylene compounds.
Hirota, Kosaku; Sajiki, Hironao; Maki, Yoshifumi; Inoue, Hideo; Ueda, Tohru. Gifu Pharm. Univ., Gifu, Japan.
Nucleic Acids Symposium Series (1986), 17(Symp. Nucleic Acids Chem., 14th, 1986), 9-12.
- Synthesis of 6-aminouracils and pyrrolo[2,3-d]pyrimidine-2,4-diones and their inhibitory effect on thymidine phosphorylase.
Hirota Kosaku; Sawada Masayuki; Sajiki Hironao; Sako Magoichi Laboratory of Medicinal Chemistry, Gifu Pharmaceutical University, Japan
Nucleic acids symposium series (1997), 37, 59-60.
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